Publications
Smith TKT, Ghorbani P, LeBlond ND, Nunes JRC, O'Dwyer C, Ambursley N, Fong-McMaster C, Minarrieta L, Burkovsky LA, El-Hakim R, Trzaskalski NA, Locatelli CAA, Stotts C, Pember C, Rayner KJ, Kemp BE, Loh K, Harper ME, Mulvihill EE, St-Pierre J, Fullerton MD. Atherosclerosis. 2024 Jun 3:117608. doi: 10.1016/j.atherosclerosis.2024.117608. Online ahead of print. PMID: 38880706
Nunes JRC, O'Dwyer C, Ghorbani P, Smith TKT, Chauhan S, Robert-Gostlin V, Girouard MD, Viollet B, Foretz M, Fullerton MD. J Lipid Res. 2024 Jun;65(6):100564. doi: 10.1016/j.jlr.2024.100564. Epub 2024 May 17. PMID: 38762124
Hoyeck MP, Angela Ching ME, Basu L, van Allen K, Palaniyandi J, Perera I, Poleo-Giordani E, Hanson AA, Ghorbani P, Fullerton MD, Bruin JE. Mol Metab. 2024 Mar;81:101893. doi: 10.1016/j.molmet.2024.101893. Epub 2024 Feb 2. PMID: 38309623
Day EA, Townsend LK, Rehal S, Batchuluun B, Wang D, Morrow MR, Lu R, Lundenberg L, Lu JH, Desjardins EM, Smith TKT, Raphenya AR, McArthur AG, Fullerton MD, Steinberg GR. iScience. 2023 Oct 20;26(11):108269. doi: 10.1016/j.isci.2023.108269. eCollection 2023 Nov 17. PMID: 38026185
Ghorbani P, Kim SY, Smith TKT, Minarrieta L, Robert-Gostlin V, Kilgour MK, Ilijevska M, Alecu I, Snider SA, Margison KD, Nunes JRC, Woo D, Pember C, O'Dwyer C, Ouellette J, Kotchetkov P, St-Pierre J, Bennett SAL, Lacoste B, Blais A, Nair MG, Fullerton MD. PLoS Pathog. 2023 Sep 25;19(9):e1011658. doi: 10.1371/journal.ppat.1011658. eCollection 2023 Sep. PMID: 37747879
Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress.
Fadzeyeva E, Locatelli CAA, Trzaskalski NA, Nguyen MA, Capozzi ME, Vulesevic B, Morrow NM, Ghorbani P, Hanson AA, Lorenzen-Schmidt I, Doyle MA, Seymour R, Varin EM, Fullerton MD, Campbell JE, Mulvihill EE. iScience. 2023 Apr 26;26(5):106748. doi: 10.1016/j.isci.2023.106748. eCollection 2023 May 19. PMID: 37216093
Nunes JRC, Smith TKT, Ghorbani P, O'Dwyer C, Trzaskalski NA, Dergham H, Pember C, Kilgour MK, Mulvihill EE, Fullerton MD. Am J Physiol Endocrinol Metab. 2023 Jul 1;325(1):E10-E20. doi: 10.1152/ajpendo.00124.2023. Epub 2023 May 17. PMID: 37196059
Trzaskalski NA, Vulesevic B, Nguyen MA, Jeraj N, Fadzeyeva E, Morrow NM, Locatelli CA, Travis N, Hanson AA, Nunes JR, O'Dwyer C, van der Veen JN, Lorenzen-Schmidt I, Seymour R, Pulente SM, Clément AC, Crawley AM, Jacobs RL, Doyle MA, Cooper CL, Kim KH, Fullerton MD, Mulvihill EE. JCI Insight. 2023 Jan 24;8(2):e154314. doi: 10.1172/jci.insight.154314. PMID: 36472923
Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity.
Pileggi CA, Blondin DP, Hooks BG, Parmar G, Alecu I, Patten DA, Cuillerier A, O'Dwyer C, Thrush AB, Fullerton MD, Bennett SA, Doucet É, Haman F, Cuperlovic-Culf M, McPherson R, Dent RRM, Harper ME. EBioMedicine. 2022 Sep;83:104192. doi: 10.1016/j.ebiom.2022.104192. Epub 2022 Aug 11.
Pham T, Walden E, Huard S, Pezacki J, Fullerton MD, Baetz K. Genetics. 2022 Jul 30;221(4):iyac086. doi: 10.1093/genetics/iyac086.
Lee MKS, Cooney OD, Lin X, Nadarajah S, Dragoljevic D, Huynh K, Onda DA, Galic S, Meikle PJ, Edlund T, Fullerton MD, Kemp BE, Murphy AJ, Loh K. Mol Metab. 2022 Jul;61:101514. doi: 10.1016/j.molmet.2022.101514. Epub 2022 May 10. PMID: 35562083
Salsalate reduces atherosclerosis through AMPKβ1 in mice.
Day EA, Ford RJ, Smith BK, Houde VP, Stypa S, Rehal S, Lhotak S, Kemp BE, Trigatti BL, Werstuck GH, Austin RC, Fullerton MD, Steinberg GR. Mol Metab. 2021 Nov;53:101321. doi: 10.1016/j.molmet.2021.101321. Epub 2021 Aug 21. PMID: 34425254
Petrick HL, Foley KP, Zlitni S, Brunetta HS, Paglialunga S, Miotto PM, Politis-Barber V, O'Dwyer C, Philbrick DJ, Fullerton MD, Schertzer JD, Holloway GP. Function (Oxf). 2020 Aug 25;1(2):zqaa013. doi: 10.1093/function/zqaa013. eCollection 2020. PMID: 34278304
Metformin again? Atheroprotection mediated by macrophage AMPK and ATF1.
Salt IP, Nunes JRC, Fullerton MD. Cardiovasc Res. 2021 Apr 23;117(5):1233-1234. doi: 10.1093/cvr/cvab065. PMID: 33681999
Stewart CM, Phan A, Bo Y, LeBlond ND, Smith TKT, Laroche G, Giguère PM, Fullerton MD, Pelchat M, Kobasa D, Côté M. PLoS Pathog. 2021 Jan 29;17(1):e1009275. doi: 10.1371/journal.ppat.1009275. eCollection 2021 Jan. PMID: 33513206
LeBlond ND, Nunes JRC, Smith TKT, O'Dwyer C, Robichaud S, Gadde S, Côté M, Kemp BE, Ouimet M, Fullerton MD. Int J Mol Sci. 2020 Nov 27;21(23):9033. doi: 10.3390/ijms21239033. PMID: 33261140
Salicylates Ameliorate Intestinal Inflammation by Activating Macrophage AMPK.
Banskota S, Wang H, Kwon YH, Gautam J, Gurung P, Haq S, Hassan FMN, Bowdish DM, Kim JA, Carling D, Fullerton MD, Steinberg GR, Khan WI. Inflamm Bowel Dis. 2021 May 17;27(6):914-926. doi: 10.1093/ibd/izaa305. PMID: 33252129
LeBlond ND, Ghorbani P, O'Dwyer C, Ambursley N, Nunes JRC, Smith TKT, Trzaskalski NA, Mulvihill EE, Viollet B, Foretz M, Fullerton MD. J Lipid Res. 2020 Dec;61(12):1697-1706. doi: 10.1194/jlr.RA120001040. Epub 2020 Sep 25. PMID: 32978273
Hepatic Choline Transport Is Inhibited During Fatty Acid-Induced Lipotoxicity and Obesity.
O'Dwyer C, Yaworski R, Katsumura S, Ghorbani P, Gobeil Odai K, Nunes JRC, LeBlond ND, Sanjana S, Smith TTK, Han S, Margison KD, Alain T, Morita M, Fullerton MD. Hepatol Commun. 2020 Apr 10;4(6):876-889. doi: 10.1002/hep4.1516. eCollection 2020 Jun. PMID: 32490323
Morrow NM, Burke AC, Samsoondar JP, Seigel KE, Wang A, Telford DE, Sutherland BG, O'Dwyer C, Steinberg GR, Fullerton MD, Huff MW. J Lipid Res. 2020 Mar;61(3):387-402. doi: 10.1194/jlr.RA119000542. Epub 2020 Jan 21. PMID: 31964763
In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism.
Gobeil Odai K, O'Dwyer C, Steenbergen R, Shaw TA, Renner TM, Ghorbani P, Rezaaifar M, Han S, Langlois MA, Crawley AM, Russell RS, Pezacki JP, Tyrrell DL, Fullerton MD. Viruses. 2020 Jan 16;12(1):108. doi: 10.3390/v12010108. PMID: 31963173
Smith TKT, Kahiel Z, LeBlond ND, Ghorbani P, Farah E, Al-Awosi R, Cote M, Gadde S, Fullerton MD. Molecules. 2019 Oct 18;24(20):3751. doi: 10.3390/molecules24203751. PMID: 31635211
McMurray F, MacFarlane M, Kim K, Patten DA, Wei-LaPierre L, Fullerton MD, Harper ME. FASEB J. 2019 Dec;33(12):13515-13526. doi: 10.1096/fj.201901150R. Epub 2019 Oct 3. PMID: 31581846
A Diacylglycerol Kinase Inhibitor, R-59-022, Blocks Filovirus Internalization in Host Cells.
Stewart CM, Dorion SS, Ottenbrite MAF, LeBlond ND, Smith TKT, Qiu S, Fullerton MD, Kobasa D, Côté M. Viruses. 2019 Mar 1;11(3):206. doi: 10.3390/v11030206. PMID: 30832223
Losier TT, Akuma M, McKee-Muir OC, LeBlond ND, Suk Y, Alsaadi RM, Guo Z, Reshke R, Sad S, Campbell-Valois FX, Gibbings DJ, Fullerton MD, Russell RC. Cell Rep. 2019 Feb 19;26(8):2150-2165.e5. doi: 10.1016/j.celrep.2019.01.062. PMID: 30784596
Almutairi SM, Ali AK, He W, Yang DS, Ghorbani P, Wang L, Fullerton MD, Lee SH. J Biol Chem. 2019 Mar 22;294(12):4644-4655. doi: 10.1074/jbc.RA118.005892. Epub 2019 Jan 29. PMID: 30696773
Loh K, Tam S, Murray-Segal L, Huynh K, Meikle PJ, Scott JW, van Denderen B, Chen Z, Steel R, LeBlond ND, Burkovsky LA, O'Dwyer C, Nunes JRC, Steinberg GR, Fullerton MD, Galic S, Kemp BE. Hepatol Commun. 2018 Nov 12;3(1):84-98. doi: 10.1002/hep4.1279. eCollection 2019 Jan. PMID: 30619997
A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling.
van der Veen JN, Lingrell S, McCloskey N, LeBlond ND, Galleguillos D, Zhao YY, Curtis JM, Sipione S, Fullerton MD, Vance DE, Jacobs RL. FASEB J. 2019 Apr;33(4):5045-5057. doi: 10.1096/fj.201802117R. Epub 2019 Jan 7. PMID: 30615497
Does prenylation predict progression in NAFLD?
Ghorbani P, Smith TK, Fullerton MD. J Pathol. 2019 Mar;247(3):283-286. doi: 10.1002/path.5190. Epub 2018 Dec 27. PMID: 30374976
Choline transport links macrophage phospholipid metabolism and inflammation.
Snider SA, Margison KD, Ghorbani P, LeBlond ND, O'Dwyer C, Nunes JRC, Nguyen T, Xu H, Bennett SAL, Fullerton MD. J Biol Chem. 2018 Jul 20;293(29):11600-11611. doi: 10.1074/jbc.RA118.003180. Epub 2018 Jun 7. PMID: 29880645
Methods to Evaluate AMPK Regulation of Macrophage Cholesterol Homeostasis.
LeBlond ND, Fullerton MD. Methods Mol Biol. 2018;1732:477-493. doi: 10.1007/978-1-4939-7598-3_30. PMID: 29480494
Sundaram M, Curtis KR, Amir Alipour M, LeBlond ND, Margison KD, Yaworski RA, Parks RJ, McIntyre AD, Hegele RA, Fullerton MD, Yao Z. J Lipid Res. 2017 Nov;58(11):2188-2196. doi: 10.1194/jlr.M077313. Epub 2017 Sep 8. PMID: 28887372
Rollins M, Huard S, Morettin A, Takuski J, Pham TT, Fullerton MD, Côté J, Baetz K. PLoS Genet. 2017 Feb 23;13(2):e1006626. doi: 10.1371/journal.pgen.1006626. eCollection 2017 Feb. PMID: 28231279
AMP-activated protein kinase and its multifaceted regulation of hepatic metabolism.
Fullerton MD. Curr Opin Lipidol. 2016 Apr;27(2):172-80. doi: 10.1097/MOL.0000000000000273. PMID: 26906549 Review.
Ouimet M, Ediriweera HN, Gundra UM, Sheedy FJ, Ramkhelawon B, Hutchison SB, Rinehold K, van Solingen C, Fullerton MD, Cecchini K, Rayner KJ, Steinberg GR, Zamore PD, Fisher EA, Loke P, Moore KJ. J Clin Invest. 2015 Oct 26;125(12):4334-48. doi: 10.1172/JCI81676. PMID: 26517695
Salicylate improves macrophage cholesterol homeostasis via activation of Ampk.
Fullerton MD, Ford RJ, McGregor CP, LeBlond ND, Snider SA, Stypa SA, Day EA, Lhoták Š, Schertzer JD, Austin RC, Kemp BE, Steinberg GR. J Lipid Res. 2015 May;56(5):1025-33. doi: 10.1194/jlr.M058875. Epub 2015 Mar 15. PMID: 25773887